MedGenMed Hematology-Oncology
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Risk for Second Nonlymphoid Neoplasms in Chronic Lymphocytic Leukemia
Improvements in selection of chemotherapeutic and/or immunotherapeutic regimens will hopefully reduce long-term complications and will allow their curative potential to be utilized.
Journal Article, November 2007
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The Role of TGF-beta-1 Protein and TGF-beta-R-1 Receptor in Immune Escape Mechanism in Bladder Cancer
This work helps us better understand one of the escape mechanisms in bladder cancer that may facilitate the reverse of tumor escape from the immune system.
Journal Article, November 2007
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Muscular Metastasis, A Rare Presentation of Non-Small-Cell Lung Cancer
Skeletal muscle metastasis as a mode of presentation of primary lung cancer is an unusual phenomenon. A brief literature review accompanies this report.
Journal Article, July 2007
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Ingestion of Superwarfarin Leading to Coagulopathy: A Case Report and Review of the Literature
This Case Report describes a patient with superwarfarin-induced coagulopathy and reviews previous cases in adults in the literature.
Journal Article, November 2006
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Biological Response Modifiers in Cancer
This article reviews various monoclonal antibodies and angiogenesis inhibitors in clinical trials, as well as upcoming potential cancer vaccines.
Clinical Case, November 2006
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Multifactorial Etiology of Cervical Cancer: A Hypothesis
The author wonders whether there is a link between long-term inhalation of cooking smoke and the development of cervical cancer.
Journal Article, November 2005
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Case Report: A Large Extramedullary Granulocytic Sarcoma as the Initial Presenting Feature of Chronic Myeloid Leukemia
The authors report a rare case of chronic myeloid leukemia that presented initially with a granulocytic sarcoma.
Journal Article, October 2005
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Benefit With Aromatase Inhibitors in the Adjuvant Setting for Postmenopausal Women With Breast Cancer
The authors review strategies for the use of aromatase inhibitors in adjuvant therapy of early breast cancer and discuss pros and cons based on results of key clinical trials.
Journal Article, August 2005
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Topics in Pediatric Leukemia -- Fanconi's Anemia: New Insights
Fanconi's anemia is the most common of the rare inherited bone marrow failure syndromes.
Journal Article, April 2005
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Topics in Pediatric Leukemia -- Hematopoietic Stem Cell Transplantation
HSCT is an effective tool in the treatment of acute leukemia, and it plays a major role in the treatment of high-risk and relapsed disease.
Journal Article, March 2005
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Topics in Pediatric Leukemia -- Acute Myeloid Leukemia
Despite all ongoing efforts to improve treatment and supportive care, childhood AML still remains a challenging disease.
Journal Article, March 2005
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Topics in Pediatric Leukemia -- Myelodysplastic and Myeloproliferative Disorders of Childhood
A recent classification addresses specific diagnostic problems and the rarity of specific disease entities in children.
Journal Article, March 2005
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Topics in Pediatric Leukemia -- Acute Lymphoblastic Leukemia and Late Effects in Long-Term Survivors
The Children's Oncology Group has developed evidence-based, clinical practice guidelines for screening of late effects in childhood cancer survivors.
Journal Article, March 2005
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Topics in Pediatric Leukemia -- Acute Lymphoblastic Leukemia
Acute leukemia is the most common childhood malignancy, which accounts for approximately one third of all pediatric cancers. The peak incidence of childhood ALL occurs between ages 3 and 4.
Journal Article, February 2005
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Time and the Biology of Aging
What determines the length of our lives and why do we age?
Journal Article, February 2005
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Phytoestrogens and Antioxidants -- Bits of Experimental Evidence
As many cancers are still challenging our best medical resources, we can only infer that there is plenty of work for all.
Journal Article, January 2005
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Brain Metastasis From Cervical Carcinoma -- A Case Report
Although a rare event, an increase in the incidence of these metastases has been noted in recent years, perhaps related to the improved treatment of the primary lesions.
Journal Article, January 2005
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Caloric Restriction and Life Expectancy
Tell me what you eat, and I'll tell you how long you'll live.
Journal Article, December 2004
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Epigenetics Changes in Cancer Cells
Which chemical modifications in the DNA of cancer cells affect expression patterns of oncogenes or tumor suppressor genes?
Journal Article, December 2004
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Genes and Autoimmune Diseases -- A Complex Inheritance
Some gene associations have been confirmed, others have been proven inconsistent or restricted to a specific population.
Journal Article, December 2004