-
Kinesigenic Paroxysmal Hemidyskinesia as the Initial Presentation of Multiple Sclerosis
This report describes 2 patients with MS who present with a rare movement disorder as their first symptom.
Journal Article, October 2006
-
Self Management of Fatal Familial Insomnia. Part 1: What Is FFI?
What causes this mysterious and relentless prion disorder? Can treatment improve a victim's life expectancy?
Journal Article, September 2006
-
Self-management of Fatal Familial Insomnia. Part 2: Case Report
This patient doubled his life expectancy after being diagnosed with this debilitating prion disorder. What therapies improved the quality and length of his life?
Journal Article, September 2006
-
Restless Legs Syndrome in Children
Symptoms of restless legs syndrome in children can be confused with other disorders. What words do children typically use to describe RLS sensations? Which signs and symptoms should tip you off to this diagnosis?
Journal Article, June 2006
-
Emerging Drugs for Migraine Prophylaxis and Treatment
Only 50% of patients with migraine attain more than 50% reduction of headache frequency after 3 months of treatment. Do any experimental agents promise to work better?
Journal Article, May 2006
-
Editorial: Cytokine Inhibition for Treatment of Alzheimer's Disease
Modulating cytokines to reduce neuronal inflammation shows promise that has thus far eluded patients with Alzheimer's disease.
Journal Article, April 2006
-
TNF-alpha Modulation for Treatment of Alzheimer's Disease: A 6-Month Pilot Study
A growing body of evidence implicates inflammatory processes and glial activation in AD pathogenesis. Results from this pilot study suggest that inhibiting TNF-alpha may be an effective therapy.
Journal Article, April 2006
-
The Cerebrospinal Venous System: Anatomy, Physiology, and Clinical Implications
The anatomic and functional continuity between veins, venous sinuses, and venous plexuses of the brain and spine has been recognized for decades. The author proposes the label "cerebrospinal venous system" to formalize this relationship.
Journal Article, February 2006
-
Lysine Clonixinate vs Naproxen Sodium for the Acute Treatment of Migraine: A Double-Blind, Randomized, Crossover Study
In developing countries, pain relief can take a backseat to cost. In this study, South American headache specialists sought a cost-effective remedy for migraine.
Journal Article, December 2005
-
Pilomyxoid Astrocytoma: A Review
Increased recognition of pilomyxoid astrocytoma within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas.
Journal Article, November 2004
-
Amyloid, Tau, and Cell Death in Alzheimer's Disease
The ying and yang of APP and tau affect neuron survival, growth, and degeneration.
Journal Article, August 2004
-
ApoE and Alzheimer's Disease -- 10 Years Later
New insights in the biological function of apoE may shed light on its putative role in the development of brain damage and cognitive impairment.
Journal Article, August 2004
-
Weight Variations in Patients Receiving Topiramate Migraine Prophylaxis in a Tertiary Care Setting
This study examined the efficacy and tolerability of topiramate in patients with migraine treated at a tertiary care headache clinic. Weight loss was a beneficial side effect for this population.
Journal Article, July 2004
-
Helmet-Related, External Compression Headache Among Police Officers in Rio de Janeiro
The external compression headache is classified as a kind of cranial neuralgia because of continued external pressure. This headache also has some peculiar characteristics.
Journal Article, May 2004
-
The Therapeutic Potential of Melatonin: A Review of the Science
This review summarizes the physiology of melatonin and discusses the potential therapeutic uses of melatonin for conditions, such as sleep disorders, cancer, seizures, among others.
Journal Article, April 2004
-
Diet and Alzheimer's Disease: What the Evidence Shows
Can improvements in diet or use of nutritional supplements help prevent Alzheimer's disease?
Journal Article, January 2004
-
Neuroethics: How To Leave the Cave Without Going Astray
"I am much more than my genes, they are not my essence, they are not my soul; is then my consciousness, my brain me?"
Journal Article, December 2003
-
Received Wisdom vs Evidence in Stroke Prevention: Carotid Stenting Will Soon Replace Endarterectomy for All Patients Requiring Such Revascularization
The authors argue that carotid stenting will soon
replace endarterectomy as a modality of treatment for
all patients requiring revascularization.
Journal Article, November 2003
-
Received Wisdom vs Evidence in Stroke Prevention: Carotid Endarterectomy Remains the Gold Standard for Patients Requiring Carotid Revascularization
What is the real evidence behind carotid stenting?
Journal Article, November 2003
-
Conference Report - Spongiform Encephalopathies: A Tale of Cannibals, Cattle, and Prions
Healthcare professionals should exert increased surveillance for transmissible Creutzfeldt-Jacob disease, both in terms of diagnosis and prevention.
Journal Article, September 2003
